“Encephalitis lethargica remains one of the most haunting medical mysteries of the twentieth century, a disease that swept across the world and then vanished as suddenly as it appeared.”

    by Worth-Boysenberry-93

    33 Comments

    1. Worth-Boysenberry-93 on

      “At its height between 1916 and 1920, it left thousands of people suspended in a strange limbo between wakefulness and paralysis. Some slept endlessly. Others stayed wide awake but could not speak, move, or express emotion. Many were fully conscious inside bodies that refused to respond, locked in a living silence they could not break.
      The illness often began innocently enough with a fever, a sore throat, a few days of fatigue, before the neurological collapse began.

      Doctors watched patients slip into rigid catatonia, develop violent tremors, or drift into dreamlike hallucinations. Survivors of the acute phase were not always fortunate.
      Many spent decades in institutions, motionless but aware, their condition unchanged year after year. When neurologist Oliver Sacks administered L-DOPA to these patients in the late 1960s, many briefly awoke after decades of stillness, revealing minds that had been alive inside frozen bodies.

      A century later, scientists still do not know the true cause. No virus or bacterium has ever been definitively linked to the epidemic, and no cure has ever been found. It remains one of medicine’s most unsettling reminders of how fragile the brain truly is.

      Added Fact: Some of the surviving patients who “awakened” under L-DOPA reported vivid memories from the decades they spent immobile, including conversations, sounds, and even changes in seasons, suggesting they were fully aware the entire time despite being unable to move or speak.”

      From historyfeels on IG.

    2. Moral of the story: don’t talk shit about a person in a coma when you’re in the same room. They have nothing to do, and will remember it forever – or, they die and haunt the shit outta you. No way to win, just keep it classy and positive.

    3. Excellent movie about this called Awakenings with Robin Williams and Robert DeNiro. Highly recommend.

    4. Awakenings is a fictionalized account of dr sachs work on this. It is gripping and sad and worth a watch.

    5. Sakowuf_Solutions on

      RIP Dr Oliver Sacks.

      Go look for interviews and content about him. He was a truly fascinating individual.

    6. I had not heard of this before so went on a deep dive. Seems like perhaps they figured out the cause of it in 2012:

      “After the publication of this compendium, an enterovirus was discovered in encephalitis lethargica cases from the epidemic.[21] In 2012, Oliver Sacks, the author of the book Awakenings, about institutionalized survivors, acknowledged this virus as the probable cause of the disease.[22][verification needed] Other sources have suggested Streptococcus pneumoniae as a cause.[23]”

    7. AGrandNewAdventure on

      There a great movie about this called Awakenings. Check it out, it’s heart breaking, but good.

    8. MmmmmisterCrow on

      Actually it’s not a mystery. We know it happened when a sloppy wizard tried to trap death but trapped the king of dreams instead.

    9. xXSN0WBL1ND22Xx on

      “Darkness imprisoning me

      All that I see

      Absolute horror

      I cannot live

      I cannot die

      Trapped in myself

      Body my holding cell”

    10. Ok_Finance_8292 on

      Oh hey the “statue disease” that essentially paralzyzed you that swept the globe in the mid 1910s to the 1920s. Sure hope this doesn’t come back up anytime soon. It won’t, right? RIGHT?

    11. What’s more amazing to me though is that the disease is still around, people are getting it, and they can’t work out what causes it. In this day and age I find it incredible that they don’t know.

    12. > Many were fully conscious inside bodies that refused to respond, locked in a living silence they could not break

      Wow, this is very similar to what I experienced when I was 27 and contracted viral meningitis. They isolated me to a negative-pressure hospital room for two months, until I began to recover (which was frankly pretty lucky – the doctors told my wife they didn’t think I’d ever be normal again).

      During most of that time I wasn’t able to interact with the world because I lost the ability to speak beyond a 4-year-old level, and I couldn’t write. They’d have me try to do simple tasks like to draw a circle and the best I could do was something that looked like an amoeba. The most frustrating thing is that I was 100% normal internally, but I just couldn’t speak with my normal vocabulary (I could only use words that I knew when I was around 4 years old). I could *think* all of the words I knew as an adult, I just couldn’t speak them out loud, and oddly I couldn’t write either, or control a pencil/pen with any accuracy. I remember trying to explain to the doctors how I could think everything normally internally but just couldn’t express it, but my four-year-old self lacked the vocabulary to do that and so I’m not sure if I even got that message across. It was very frustrating.

      After I began to recover it took a while for me to regain/relearn how to talk, walk, etc. And the pain kind of went on for about a year after that such that I wasn’t able to lie down to sleep (too painful) and had to lean up against the wall at night. Not my fav experience. But also not my worst experience. That came later… lol. This life can be a bit challenging.

    13. I heard it was because an old magic guy was trying trap Death, but accidentally caught her younger brother Dream. Kept him locked in a bottle in the basement for 70 years.

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