CRISPR therapy is the first to permanently remove HIV

    by BradolfPittler1

    17 Comments

    1. BradolfPittler1 on

      Scientists have achieved a monumental milestone in medicine: using CRISPR gene-editing technology to remove HIV DNA from infected human cells permanently. Unlike traditional treatments that suppress the virus, this therapy targets and excises the viral genome, preventing HIV from returning.
      The breakthrough, demonstrated in laboratory settings, could revolutionize the fight against AIDS, potentially providing a functional cure. CRISPR’s precision allows it to selectively remove harmful sequences without damaging healthy DNA, a feat that opens doors for treating other genetic diseases as well.
      While human trials are still in the early stages, this development represents a beacon of hope for millions living with HIV worldwide. It showcases the transformative power of genetic engineering in curing diseases previously thought incurable.

    2. Honestly that’s amazing and it’s fantastic news… But Crispr sounds like an airfryer or something.

    3. CraziestMoonMan on

      Awesome now roll it out and eradicate the virus…oh wait I forgot we live in a world that values profits over actually helping the world.

    4. Choice-Implement1643 on

      The very fact that it’s news means it’s already ready to roll out for a hefty price tag. Had the inventor intended for it to be free then he/she would have already been found at the bottom of a lake with their data destroyed in an “accidental fire”.

    5. Melodic_Mulberry on

      But to make it work in a body instead of a petri dish, we need to turn it into a virus. That’s not happening any time soon.

    6. SkyImaginationLight on

      This sounds promising. I would like to see them use this method against cancer cells.

    7. invisibledeoderant on

      This method has been being studied since at least 2023, and there are several phase 1 and 2 trials going on as of now, but so far they seem successful. Only after phase 3 and 4 studies can the FDA approve a treatment for use on the general public in the US. So definitely awesome news, but it’ll take a few years for this gene therapy to start being used widespread

    8. Yeah so this was likely done in the lab, with cell cultures.
      Although impressive, there is A LOT of work to be done to apply this in a human. How will we reach all cells in the body that are affected? And, side effects of non-specific CRISPR cuts….

    9. I can’t find anything out there about CRISPR actively cutting the HIV cells out of living cells, so I don’t know what this sensationalist article is. I’m even more dubious since OP never actually answered the post when asked for the study.

      I did find these though:

      https://www.aidsmap.com/news/oct-2025/turning-hivs-power-against-itself-may-help-target-hidden-virus-another-step-towards

      This one is months old:
      https://www.theguardian.com/global-development/2025/jun/05/breakthrough-in-search-for-hiv-cure-leaves-researchers-overwhelmed

      This was from the start of the year:
      https://www.mdpi.com/2075-1729/15/2/276

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